COMBINATION OF CRIZOTINIB AND OSIMERTINIB IN T790M+ EGFR-MUTANT NON-SMALL CELL LUNG CANCER WITH EMERGING MET AMPLIFICATION POST-OSIMERTINIB PROGRESSION IN A 10-YEAR SURVIVOR: A CASE REPORT

Tyrosine kinase inhibitors (TKIs) Fridge Crisper Bin Support represent the standard treatment for patients with non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations.The duration of the response is, however, limited in time owing to the development of resistance mechanisms to both first- and second-generatio

An increasing number of Conditionally Automated Driving (CAD) systems Collections are being developed by major automotive manufacturers.In a CAD system, the automated system is in control of the vehicle within its operational design domain.Therefore, in CAD the vehicle is capable of tactical control of the vehicle and needs to be able to maneuver e

The article presents issues relevant to the cognitive theory of metaphor developed by G.Lakoff and M.Johnson.The researchers suggest that metaphors are common.They are rooted in the experience, important in the perception of the world, thinking, acting, as revealed in the language.The metaphor of language is a reflection of a conceptual metaphor.La

The paper deals with the control device for a uniaxial trailer, which makes it possible to increase the maneuverability and reliability of the movement of a low-tonnage roadtrain by using flexible coupling in the hitch mechanism.This makes it possible to use roadtrain at emergency situations, in narrow urban streets, in greenhouses, livestock house